Methods, systems and computer programs for assessing chd...

G - Physics – 01 – N

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G01N 33/92 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2542107

Methods, computer program products and apparatus determine a subject's risk of having or developing CHD using a mathematical model of in vivo concentration of LDL particles using concentration gradient factors to adjust in vitro measurements of small and large LDL particles to reflect predicted internal concentrations to thereby provide an improved model of CHD risk.

L'invention concerne des procédés, des produits de programmes informatiques et des appareils permettant de déterminer le risque d'un sujet d'avoir ou de développer une CHD, au moyen d'un modèle mathématique de concentration in vivo de particules de LDL mettant en oeuvre des facteurs de gradients de concentration permettant d'ajuster des mesures in vitro de petites et grandes particules de LDL, aux fins de réflexion de concentrations internes prévues permettant d'obtenir un modèle amélioré du risque d'avoir ou de développer une CHD.

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