C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/74 (2006.01) C12Q 1/02 (2006.01) C12Q 1/25 (2006.01) G01N 33/53 (2006.01) G01N 33/554 (2006.01) G01N 33/567 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2207103
In various aspects of the present invention, carbohydrate ligands and peptide mimetopes of such ligands are provided which specifically bind to leczymes, and leczymes are provided which specifically bind to carbohydrate ligands and peptide mimetopes. Other aspects of the invention include methods for identifying, purifying and producing such carbohydrates, mimetopes and leczymes, and the use of such compositions in treating various diseases and otherwise modifying the functions of cells. Still other aspects of the invention involve diagnosis of various diseases involving carbohydrate ligands, peptide mimetopes of such ligands, and/or leczymes.
Cette invention concerne, sous divers aspects, des ligands contenant des hydrates de carbone et les mimétopes peptidiques de ces ligands, lesquels se lient spécifiquement à des leczymes. Cette invention concerne également des leczymes se liant spécifiquement à des ligands contenant des hydrates de carbone et à des mimétopes peptidiques. Cette invention prévoit en outre des procédés d'identification, de purification et de fabrication desdits hydrates de carbone, mimétopes et leczymes, ainsi que l'utilisation de telles compositions dans le traitement de diverses maladies, voire même dans la modification des fonctions cellulaires. Cette invention concerne enfin le diagnostic de diverses maladies à l'aide de ligands à base d'hydrates de carbone, de mimétopes peptidiques de ces ligands et/ou de leczymes.
Ridout & Maybee Llp
Rothenberg Barry E.
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