Methods to increase blood flow to ischemic tissue

A - Human Necessities – 61 – K

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Details

A61K 38/08 (2006.01) C07K 7/14 (2006.01) C12N 5/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2339330

The present invention provides methods and kits for increasing blood flow to ischemic tissue, comprising the administration of an effective amount of angiotensinogen, angiotensin I (AI), AI analogues, AI fragments and analogues thereof, angiotensin II (AII), AII analogues, AII fragments or analogues thereof or AII AT2 type 2 receptor agonists.

La présente invention concerne des procédés et des trousses qui permettent d'augmenter le débit sanguin vers le tissu ischémique. Les procédés consistent à administrer une quantité effective d'angiotensinogène, de l'angiotensine I (AI), d'analogues de l'AI, de fragments de l'AI ou d'analogues desdits fragments, de l'angiotensine II (AII), d'analogues de l'AII, de fragments de l'AII ou d'analogues desdits fragments, ou d'agonistes du récepteur de l'AII AT¿2? type 2.

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