Methods to reduce b-helper t cells to treat autoimmune diseases

Details Methods to reduce b-helper t cells to treat autoimmune diseases Methods to reduce b-helper t cells to treat autoimmune diseases

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 17/00 (2006.01) A61P 19/02 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2738660

The present invention includes compositions and methods for the treatment of autoimmune diseases by administering to a subject having an autoimmune disorder an effective amount of a therapeutic composition comprising a pharmaceutically acceptable carrier and at least one IL- 12 inhibitor, e.g., a blocking anti-IL- 12 antibody or fragment thereof.

La présente invention concerne des compositions et des procédés pour le traitement de maladies auto-immunes par l'administration à un sujet atteint d'un trouble auto-immun d'une quantité efficace d'une composition thérapeutique comportant un support pharmaceutiquement acceptable et au moins un inhibiteur de l'IL-12, par exemple, un anticorps de blocage anti-IL-12 ou un fragment de celui-ci.

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