Methods to trigger, maintain and manipulate immune responses...

A - Human Necessities – 61 – K

Patent

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A61K 39/00 (2006.01)

Patent

CA 2592922

The present invention includes use of a biological response modifier (BRM) to modulate an immune response in a subject while avoiding or limiting common side-effects associate with BRM use. The BRMs of the present invention can be injected into a secondary lymphatic organ of the subject or into an area of relatively high drainage into a secondary lymphatic organ of the subject. The modulated immune response can be general or antigen-specific.

L'invention concerne l'utilisation de modificateurs de réponse biologique (BRM) permettant de moduler une réponse immunitaire chez un sujet tout en évitant ou limitant les effets secondaires communs associés à l'utilisation de ces BRM. Les BRM de l'invention peuvent être injectés dans organe lymphatique secondaire du sujet ou dans une zone de drainage relativement élevé à l'intérieur d'un organe lymphatique secondaire du sujet. La réponse immunitaire modulée peut être générale ou spécifique d'un antigène.

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