Methods using a combination of a 3-heteroaryl-2-indolinone...

Details Methods using a combination of a 3-heteroaryl-2-indolinone... Methods using a combination of a 3-heteroaryl-2-indolinone...

A - Human Necessities

61

K

A61K 31/4045 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/5375 (2006.01) A61K 31/675 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2484324

The present invention provides methods and compositions useful for treatment or prevention of neoplasia by administering a combination comprising a 3- heteroaryl-2-indolinone compound and a COX-2 selective inhibitor. Further provided are compositions, pharmaceutical compositions, and kits for treatment and prevention of neoplasia.

L'invention concerne des procédés et des compositions utiles pour le traitement ou la prévention de la néoplasie reposant sur l'administration d'une combinaison de 3-hétéroaryle-2-indolinone et d'inhibiteur sélectif de cyclo-oxygénase-2 (COX-2). L'invention concerne également des compositions, des compositions pharmaceutiques et des kits pour le traitement et la prévention de la néoplasie.

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