Methyl ¬5-(2-thienylhydroxymethyl)-1h-...

C - Chemistry – Metallurgy – 07 – D

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260/305.05

C07D 409/06 (2006.01) C07D 235/32 (2006.01) C07D 409/10 (2006.01)

Patent

CA 1145340

METHYL [5-(2-THIENYLXYDROXYMETHYL)-1H- BENZIMIDAZOL-2-YL]CARBAMATE, PROCESS FOR ITS PREPARATION AND COMPOSITIONS CONTAINING IT. ABSTRACT Methyl [5-(2-thienylhydroxymethyl)-1H-benzimi- dazol-2-yl]carbamate is a potent antimitotic agent. It can be prepared by reduction of methyl [5-(2-thenoyl)- 1H-benzimidazol-2-yl]carbamate. The invention also provides antimitotic compositions containing the compound of the invention.

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