Methyl analogs of simvastatin as novel hmg-coa reductase...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 309/30 (2006.01) A61K 31/215 (2006.01) A61K 31/225 (2006.01) A61K 31/35 (2006.01) A61K 31/366 (2006.01) A61P 3/06 (2006.01) C07C 69/03 (2006.01) C07C 69/30 (2006.01)

Patent

CA 2450617

The present invention relates to a novel methyl analog of simvastatin, which has the ability to inhibit the synthesis of cholesterol. The compound of the present invention holds promise for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders. The invention also relates to a process for making the novel compound.

La présente invention concerne un nouvel analogue méthyle de simvastatine qui est capable d'inhiber la synthèse du cholestérol. Ce composé est prometteur pour le traitement et la prophylaxie de l'hypercholestérolémie et de diverses pathologies cardiaques. Cette invention concerne aussi un processus de fabrication de ce nouveau composé.

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