C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/08 (2006.01)
Patent
CA 2675041
The present invention relates to a method of producing methyl esters of a hyaluronic acid, said method comprising the steps of: (a) providing a suspension comprising the acid form of the hyaluronic acid in methanol; (b) adding an organic solution of trimethylsilyldiazomethane to the suspension and mixing, whereby methyl esters of hyaluronic acid are produced; and (c) recovering the hyaluronic acid methyl esters.
La présente invention concerne une méthode de production d'esters méthyliques d'acide hyaluronique, ladite méthode comprenant les étapes suivantes : (a) obtention d'une suspension constituée de la forme acide de l'acide hyaluronique dans du méthanol ; (b) ajout d'une solution organique de triméthylsilyldiazométhane à la suspension et mélange, entraînant la production d'esters méthyliques d'acide hyaluronique ; et (c) récupération des esters méthyliques d'acide hyaluronique.
Gross Richard A.
Kumar Vineet
Longin Fanny
Schwach-Abdellaoui Khadija
Novozymes Biopharma Dk A/s
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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