Methyl-quinoxaline-1,4-dioxide derivatives

Details Methyl-quinoxaline-1,4-dioxide derivatives Methyl-quinoxaline-1,4-dioxide derivatives

C - Chemistry, Metallurgy

07

D

260/251, 260/265

C07D 241/52 (2006.01) A23K 1/16 (2006.01) A23K 1/17 (2006.01) C07D 241/42 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)

Patent

CA 1177486

ABSTRACT OF THE DISCLOSURE The invention relates to fodder additives, fodder concentrates and fodders with weight gain increasing and fodder utilization improving effects, which contain as active agent a new compound of the general formula (I), Image (I) wherein R1 stands for hydrogen or lower alkyl, R2 is hydroxy and R3 is hydrogen, or R2 and R3 form together a valence bond, Q represents a carbon or nitrogen atom, A is hydrogen, hydroxymethyl, lower alkyl, phenyl-lower alkyl or lower alkoxycarbonyl, n is 0 or 1, B stands for nitro, cyano, halogen, optionally halogeno- or nitro-substituted phenyl, pyridyl, quinolyl or a group of the general formula (IV), Image (IV) in which R5 is hydrogen or lower alkylcarbonyl and R4 stands for nitro, amino, trifluoromethyl, lower alkyl or lower alkoxy, or - 2 - A and B, together with the adjacent carbon atom to which they are attached, form a 5- or 6-membered, optionally substituted heterocyclic ring which contains not more than two identical or different nitrogen and/or oxy- gen and/or sulfur heteroatom(s) and optionally one or two exocyclic oxygen atom(s) and/or sulfur atom(s) and/or imino group(s), with the proviso that if Q represents a nitrogen atom, n is 0 and B stands for a group of the general formula (IV), and with the further proviso that if Q represents a carbon atom, B is other than a group of the general formula (IV), or a biologically acceptable acid addition salt of a compound of the general formula (I) with basic character, together with appropriate inert, solid or liquid carriers or diluents. The invention also relates to a process for the pre- paration of compounds having the general formula (I) by react- ing a compound of the general formula (II), Image (II) wherein Z is oxygen atom or represents two lower alkyoxy groups and R1 is as defined above, with a compound of the general formula (III), Image (III) wherein Q, A, B and n are as defined above, and, if desired, converting the resulting compound of the general formula (I) into another compound of the general formula (I) by well-known reactions. The compounds of the general formula (I) are new.

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