Methylation assay

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01)

Patent

CA 2750979

The present invention discloses a method of generating subsets of methylation specific markers from a set, having diagnostic power for various diseases, e.g. cancer of thyroid, breast, colon, or leukemia, in diverse samples; identified subsets of that set, as well as methods for the prognosis and diagnosis of diseases.

La présente invention concerne un procédé de génération de sous-ensembles de marqueurs spécifiques à la méthylation, parmi un sous-ensemble de marqueurs, et ayant un pouvoir diagnostic pour différentes pathologies, telles que le cancer de la thyroïde, du sein, du colon ou la leucémie, dans divers échantillons. L'invention concerne également des sous-ensembles identifiés de cet ensemble, ainsi que des procédés de pronostic et de diagnostic de pathologies.

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