C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/44 (2006.01) A61K 38/17 (2006.01) C07K 16/18 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2266760
The subject invention provides for methods of assaying arginine methyltransferase activity by means of measuring the methylation of SLM-1, SLM-2. Sam68, hnRNP K, WASP or derivatives thereof. Measurement of SLM-1, SLM-2, Sam68, hnRNP K, or WASP methylation may be used to determine whether or not a cell is cancerous. The methylation of WASP protein may also be used as a diagnostic tool for individuals with the Wiskott-Aldrich Syndrome.
Richard Stephane
Smart & Biggar
The Sir Mortimer B. Davis - Jewish General Hospital
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