C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/24 (2006.01) C07D 209/08 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2405937
A process for manufacturing a methylated indole compounds of formula (I) from the non-methylated precursor with dimethyl carbonate in the presence of a base and/or catalyst at ambient pressure wherein R1 and R2 are defined in the description and claims.
L'invention concerne un procédé de fabrication d'un composé d'indole méthylé selon la formule (I). Ce composé est fabriqué à partir du précurseur non méthylé avec du diméthylcarbonate en présence d'une base et/ou d'un catalyseur à une pression ambiante où R<1> et R<2> sont définis dans le descriptif et les revendications.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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