C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07K 14/81 (2006.01) C12Q 1/34 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2612690
The present invention provides a method of PCR, methylation specific PCR (MSP), for rapid identification of DNA methylation patterns in a CpG-containing nucleic acid. MSP uses the PCR reaction itself to distinguish between methylated and unmethylated DNA, which adds an improved sensitivity of methylation detection.
Baylin Stephen B.
Herman James G.
Mbm Intellectual Property Law Llp
The Johns Hopkins University School Of Medicine
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