Methylene blue for the treatment or prophylaxis of...

Details Methylene blue for the treatment or prophylaxis of... Methylene blue for the treatment or prophylaxis of...

A - Human Necessities

61

K

A61K 31/675 (2006.01) A61K 31/44 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2176386

The encephalopathy caused by ifosfamide and similarly acting compounds can be prevented or treated by the administration of methylene blue or another compound which is able to oxidise a reduced flavin moiety. Pyritinol is able to reduce other aspects of ifosfamide toxicity.

On peut prévenir ou traiter l'encéphalopathie causée par l'ifosfamide et par des composés présentant une activité similaire, en administrant du bleu de méthylène ou un autre composé capable d'oxyder une fraction réduite de flavine. Le pyritinol peut également diminuer d'autres aspects de la toxicité de l'ifosfamide.

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