C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/56 (2006.01) A61K 31/455 (2006.01) A61P 35/00 (2006.01) C07D 213/81 (2006.01)
Patent
CA 2591332
This invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof; a pharmaceutical composition; a method of treating a disease mediated by an MMP-13 enzyme in a mammal; and a therapeutic combination containing at least two pharmaceutically active components, wherein R1 , Q, W1 , W2 , R2a , R3a , R3b, L1, and L2, the pharmaceutical composition, the method of treating, and the therapeutic combination are as defined in the specification.
L'invention concerne un composé ayant la formule (I) ou son sel pharmaceutiquement acceptable; une composition pharmaceutique; un procédé pour traiter une maladie à médiation par une enzyme MMP-13 chez un mammifère; et une combinaison thérapeutique comprenant au moins deux composants pharmaceutiquement actifs, R1, Q, W1, W2, R2a, R3a, R3b, L1, et L2, la composition pharmaceutique, le procédé de traitement et la combinaison thérapeutique étant définis dans la description.
Booth Richard John
O'brien Patrick Michael
Booth Richard John
O'brien Patrick Michael
Smart & Biggar
Warner-Lambert Company Llc
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