Methylidene-d-xylopyranosyl-substituted and...

Details Methylidene-d-xylopyranosyl-substituted and... Methylidene-d-xylopyranosyl-substituted and...

C - Chemistry, Metallurgy

07

H

C07H 7/04 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2572819

D-xylopyranosyl-substituted phenyls of general formula (I), in which radicals R1 to R5, X, Z as well as R7a, R7b and R7c are defined as in Claim 1, exhibit an inhibiting effect upon the sodium-dependent glucose-cotransporter SGLT. The invention also relates to medicaments for treating metabolic diseases.

L'invention concerne des phényles substitués par D-xylopyranosyle de formule générale (I), les restes R1 à R5, X, Z, ainsi que R7a, R7b, R7c étant définis comme dans la revendication 1. Lesdits composés présentent une effet inhibiteur sur le cotransporteur glucose sodium-dépendant SGLT. L'invention concerne également des médicaments permettant de traiter des maladies métaboliques.

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