Mevalonate kinase as a target for fungicides

Details Mevalonate kinase as a target for fungicides Mevalonate kinase as a target for fungicides

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 9/12 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2514694

The invention relates to the preparation of mevalonate kinase as a target for fungicides, to the preparation of novel nucleic acid sequences and functional equivalents thereof, and to the use of the gene products of the cited nucleic acid sequences as novel targets for fungicides. The invention also relates to methods for identifying fungicides inhibiting a polypeptide having the biological activity of a mevalonate kinase, and to the use of the compounds identified by means of the above-mentioned method as fungicides.

L'invention concerne l'utilisation d'une mévalonate-kinase comme cible pour des fongicides, l'utilisation de nouvelles séquences d'acides nucléiques, d'équivalents fonctionnels desdites séquences d'acides nucléiques ainsi que l'utilisation des produits géniques desdites séquences d'acides nucléiques comme nouvelles cibles pour des fongicides. L'invention concerne en outre un procédé pour identifier des fongicides qui inhibent un polypeptide présentant l'activité biologique d'une mévalonate-kinase ainsi que l'utilisation comme fongicides des composés identifiés selon le procédé mentionné ci-dessus.

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