Mg53 compositions and methods of use

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01N 37/18 (2006.01) A61K 8/98 (2006.01) A61K 38/17 (2006.01) A61P 17/02 (2006.01) A61P 21/00 (2006.01) A61P 41/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2657319

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acide nucléique qui encodent de nouveaux polypeptides. Des polypeptides encodés par ces séquences d'acide nucléique, et des anticorps, qui se lient de manière immunospécifique au polypeptide, de même que des dérivés, variantes, mutants ou fragments du polypeptide, polynucléotide ou anticorps mentionnés ci-dessus sont également décrits. L'invention concerne en outre des procédés thérapeutiques de diagnostic et de recherche pour diagnostiquer, traiter et empêcher des troubles impliquant un quelconque de ces nouveaux acides nucléiques humains et de ces nouvelles protéines.

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