C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/04 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2430896
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of tuberculosis, and discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against tuberculosis. The peptide and/or proteins of the invention may be used as a therapeutic drug to stimulate the immune system to recognize and eliminate M.tuberculosis in infected cells or as a vaccine for the prevention of disease. Antibodies that react with the immunogens of the invention, as well as methods of using these antibodies for prevention and treatment of disease, are also disclosed.
L'invention porte sur des compositions et des procédés visant à prévenir, traiter et diagnostiquer la tuberculose, et sur des peptides, polypeptides et polynucléotides qui peuvent être utilisés pour stimuler une réponse immune induite par les lymphocytes T cytotoxiques contre la tuberculose. Les peptides et/ou protéines de l'invention peuvent être utilisés comme médicament thérapeutique pour stimuler le système immun afin de reconnaître et éliminer <i>M.tuberculosis</i> dans les cellules infectées, ou comme vaccin dans la prévention de la maladie. L'invention porte également sur des anticorps qui réagissent avec les immunogènes de l'invention, ainsi que sur des procédés d'utilisation de ces anticorps dans la prévention et le traitement de la maladie.
Engelhard Victor H.
Flyer David
Hunt Donald F.
Philip Ramila
Ross Mark M.
Argonex Pharmaceuticals Inc.
Smart & Biggar
University Of Virginia Patent Foundation
LandOfFree
Mhc class i associated peptides for prevention and treatment... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mhc class i associated peptides for prevention and treatment..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mhc class i associated peptides for prevention and treatment... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1673528