C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/635 (2006.01) A61L 27/18 (2006.01) C08L 71/02 (2006.01)
Patent
CA 2592040
The invention features synthetic biomaterials and methods for their formation having incorporated bioactive factors whereby the bioactive factor is covalently bound to the biomaterial by an enzymatically degradable linkage. These biomaterials may be used for localized delivery of pharmaceutically active ingredients, the bioactive factors, for tissue repair and regeneration and in particular for regeneration of soft and hard tissue, such as skin, bone, tendons and cartilage.
L'invention concerne des biomatériaux synthétiques et des procédés de formation desdits biomatériaux synthétiques auxquels sont incorporés des facteurs bioactifs, ces derniers étant liés par covalence aux biomatériaux par une liaison dégradable par voie enzymatique. Ces biomatériaux peuvent être utilisés pour l'administration localisée d'ingrédients actifs sur le plan pharmaceutique, des facteurs bioactifs, pour la réparation et la régénération de tissus et en particulier la régénération de tissus mous et de tissus durs de type cutanés, osseux, tendineux et cartilagineux.
Cowling Didier
Lutolf Matthias
Rehor Annemie
Schense Jason
Kuros Biosurgery Ag
Mcfadden Fincham
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