Micro-globule metering and sampling structure and microchips...

G - Physics – 01 – N

Patent

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Details

G01N 1/10 (2006.01) B01F 5/04 (2006.01) B01F 13/00 (2006.01) B01F 15/02 (2006.01) B01L 3/00 (2006.01) G01N 1/00 (2006.01) G01N 30/96 (2006.01) G01N 37/00 (2006.01)

Patent

CA 2408692

An improved structure has a first channel and a second channel that extend in specified directions, a third channel open in a wall of said first channel and a fourth channel that is open to a wall of said second channel such that it couples an end of said third channel to said second channel, that has a property of being less wettable (or insensitive to capillary attraction) and that is narrower than the other three channels; a liquid introduced into said first channel is drawn into said third channel and thereafter said liquid that remains in said first channel is removed to meter and sample a volume of globule equal to the capacity of said third channel. If the second channel is already filled with a liquid, the structure is modified to further include a fifth channel that is open to a wall of said fourth channel, that is narrower than or equal in thickness to said fourth channel and that is made of a wall having a property of being less wettable (or insensitive to capillary attraction).

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