C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2374406
Solid phase polymerase-mediated amplification approaches using immobilized primers on a microarray are provided for detecting sequence variations in a target polynucleotide. The methods and compositions provided herein are useful for research and clinical applications, particularly for large scale assays of genetic information in biological samples of interest.
La présente invention concerne des procédés d'amplification à médiation polymérase en phase solide, dans lesquels on utilise des amorces immobilisés sur un micro-échantillon pour détecter les variations de séquences dans un polynucléotide cible. Les procédés et compositions de cette invention sont utilisés dans la recherche et dans les applications cliniques, en particulier pour les criblages à large échelle d'informations génétiques dans des échantillons biologiques recherchés.
Hu Qianjin
Peng Zaoyuan
Yu Zailin
Borden Ladner Gervais Llp
Mergen Ltd.
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