C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 33/10 (2006.01)
Patent
CA 2240315
The invention relates to a microbial method of in vitro transformation of a steroid into its corresponding 11.alpha.-hydroxy analogue using oxygen and a microorganism selected from Aspergillus ochraceus, Aspergillus niger, Rhizopus stolonifer, Rhizopus nigricans, Rhizopus arrhizus, and strains of Pestelotia, characterized in that a steroid having a purity of less than 97 % is used.
L'invention concerne un procédé microbien de transformation in vitro d'un stéroïde en son analogue 11.alpha.-hydroxy correspondant, à l'aide d'oxygène et d'un micro-organisme choisi parmi Aspergillus ochraceus, Aspergillus niger, Rhizopus stolonifer, Rhizopus nigricans, Rhizopus arrhizus, et parmi des souches de Pestelotia, ce procédé étant caractérisé en ce que l'on utilise un stéroïde possédant une pureté inférieure à 97 %.
Van Der Meijden Pieter
Wiersma Marten
Akzo Nobel N.v.
Akzo Nobel Nv
Fetherstonhaugh & Co.
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