Microbial co-culture production of propionic acid

Details Microbial co-culture production of propionic acid Microbial co-culture production of propionic acid

C - Chemistry, Metallurgy

12

P

195/133, 195/34.

C12P 39/00 (2006.01) C12N 1/20 (2006.01) C12P 7/52 (2006.01)

Patent

CA 1276576

ABSTRACT OF THE DISCLOSURE A simultaneous sequential anaerobic fermentation process for the in vitro production of propionic acid and acetic acid is disclosed. The process comprises employing an obligatory two- component co-culture which maintains a relatively constant ratio of species populations over multiple passages. A first co- culture component is a Lactobacillus or Streptococcus which homofermentatively converts the hexose to lactic acid. A second microorganism in the co-culture is a Veillonella which is metabolically incapable of assimilating the hexose and converts the lactic acid product to propionic acid and acetic acid. The co-culture is inoculated into a nutrient growth feedstock, such as whole whey or a clarified dairy whey lactose permeate, which contains a metabolizable source of a hexose, such as glucose. lactose or sucrose.

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