Microbial expression of interleukin ii

Details Microbial expression of interleukin ii Microbial expression of interleukin ii

C - Chemistry, Metallurgy

12

N

530/13, 195/40,

C12N 15/26 (2006.01) C07H 21/04 (2006.01) C07K 14/55 (2006.01) C12N 9/96 (2006.01) C12N 15/69 (2006.01) C12N 15/70 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 1340872

Disclosed is the manufacture of DNA sequences comprising structural genes coding for a polypeptide having the amino acid sequence and properties of Inter-leukin II and for polypeptide analogs of Interleukin II which differ from the naturally-occurring forms in terms of the identity and/or location of one or more amino acids, e.g., [Ser125]IL-II, (G1n26]IL-II, [Phe121]IL-II, and [Stop121]IL-II.

460745

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