Microbial or enzymatic production of cyclopentene diol and...

C - Chemistry – Metallurgy – 12 – P

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C12P 1/00 (2006.01) C07C 35/06 (2006.01) C07C 45/67 (2006.01) C07D 309/12 (2006.01) C07F 7/18 (2006.01) C12N 9/18 (2006.01) C12P 7/38 (2006.01) C12P 41/00 (2006.01)

Patent

CA 1074240

ABSTRACT OF THE DISCLOSURE New optically active cyclopentene-diol and the mono- or diacyl esters thereof and a process for converting a diacyl ester of cyclopent-1-en-3,5-diol to its monoacyl ester and/or its diol which comprises subjecting a diacyl ester of cyclopent-1-en-3,5- diol containing at least one of the optically active or inactive diacyl ester of transcyclopent-1-en-3,5-diol (trans-isomer) and diacyl esters of cis-cyclopent-1-en-3,5-diol (cis-isomer), to the action of a microorganism or enzyme having at least a selectively in its rates of hydrolyzing the acyloxy group of (R) configuration and the acyloxy group of (S) configuration of said diacyl ester. There new compounds are valuable as starting materials for the preparation of prostaglandin or its analogues. - 1 -

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