Microbial process for producing cholanic acid derivatives...

Details Microbial process for producing cholanic acid derivatives... Microbial process for producing cholanic acid derivatives...

C - Chemistry, Metallurgy

12

P

195/21, 195/34.7

C12P 33/00 (2006.01) C12N 1/20 (2006.01)

Patent

CA 1169795

Abstract of the disclosure: The invention relates to a microbial process for producing a cholanic acid derivative of the formula: Image wherein X is Image or =O; and R is hydrogen, an alkali metal or an alkaline earth metal. The process com- prises cultivating a microbe selected from the genera Arthrobacter, Brevibacterium and Corynebacterium which is capable of growing in a medium containing cholic acid or a salt thereof as a substrate to produce the cholanic acid derivative in a culture medium containing the sub- strate, and collecting the resulting derivative. The process operates effectively with mediums varying widely in the concentration of the substrate.

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