Microbiological process for hydroxylation of...

C - Chemistry – Metallurgy – 12 – P

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C12P 17/12 (2006.01) C07D 213/80 (2006.01) C07D 241/24 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2091005

A microbiological process for the production of hydroxy-substituted nitrogen-containing heterocyclic carboxylic acids of the general formula: (see formula I) and the soluble salts thereof, where R1 and R2 are the same or different and each represents a hydrogen atom, a halogen atom or a C1-C4 alkyl group, and X is a nitrogen atom or a CR3 group, where R3 is a hydrogen atom or a halogen atom. The process uses the corresponding nitrogen-containing heterocyclic carboxylic acids as a starting material. Microorganisms suitable for use in the process are also described.

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