Microbiological process for the preparation of...

Details Microbiological process for the preparation of... Microbiological process for the preparation of...

C - Chemistry, Metallurgy

12

P

C12P 17/12 (2006.01)

Patent

CA 2177651

A microbiological process for the preparation of heteroaromatic carboxylic acids or physiologically tolerated salts thereof, of the general formulae: Image in which R1 and R2 are identical or different and denote a hydrogen or halogen atom and X denotes a nitrogen atom or -CH-, is described herein. The conversion is carried out in such a way that heteroaromatic nitriles of the general formulae: Image in which R1, R2 and X are as previously defined, are converted as substrate, using 2-cyanopyridine-utilizing microorganisms of the genus Alcaligenes which have been cultured before the biotransformation in the presence of a dicarboxylic acid, tricarboxylic acid or a carbohydrate, into the corresponding carboxylic acid, and the latter is converted where appropriate into a physiologically tolerated salt thereof.

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