A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61K 9/00 (2006.01) A61K 47/02 (2006.01) A61K 47/08 (2006.01) A61K 47/12 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2355293
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
L'invention concerne des formules de gamma-hydroxybutyrate dans un milieu aqueux, qui résistent à la prolifération microbienne. L'invention porte également sur des formules de gamma-hydroxybutyrate qui résistent également à la conversion en GBL. Elle se rapporte encore à des méthodes de traitement de troubles du sommeil, dont la narcolepsie, à l'aide de ces formules stables de GHB, ainsi qu'à des méthodes de traitement du sevrage alcoolique et aux opiacées, des taux réduits d'hormone de croissance, de la pression intracrânienne accrue et de la douleur physique chez un patient.
Cook Harry N.
Danielson Doug
Goderstad Colette
Hamilton Martha
Reardan Dayton
Goudreau Gage Dubuc
Orphan Medical Inc.
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