C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/20 (2006.01) G01N 33/53 (2006.01) G01N 33/531 (2006.01) G01N 33/537 (2006.01) G01N 33/543 (2006.01) G01N 33/544 (2006.01) G01N 33/546 (2006.01) G01N 33/547 (2006.01) G01N 33/552 (2006.01)
Patent
CA 2585675
The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity molecule. In addition, the invention provides glass microbubbles coated with an affinity molecule. Methods of using the microbubbles of the invention for isolating analytes and cells are specifically provided.
La présente invention concerne des procédés, des compositions et des kits utilisés dans l'isolation par affinité, la purification par affinité et le dosage par affinité sur la base de microbulles recouvertes d'une molécule d'affinité. L'invention porte notamment sur des microbulles de protéines recouvertes d'une molécule d'affinité. L'invention porte, de plus, sur des microbulles de verre recouvertes d'une molécule d'affinité, et de manière spécifique, sur des procédés d'utilisation des microbulles de l'invention dans l'isolation d'analytes et de cellules.
Adams Thomas
Jablonski Edward
Iris Molecular Diagnostics Inc.
Smart & Biggar
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