Microcarrier cell culture reactor system

C - Chemistry – Metallurgy – 12 – N

Patent

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195/141, 195/46,

C12N 5/02 (2006.01) C07K 14/555 (2006.01) C12M 3/02 (2006.01) C12N 9/72 (2006.01) C12P 1/00 (2006.01)

Patent

CA 1155072

Abstract of the Disclosure Anchorage-dependent cells are grown in agitated microcarrier suspension in which the cells and micro- carriers are aggregated by periodically providing a tem- porary residence of said microcarriers and cells outside the main cell culture reactor agitation zone and in a separate compartment wherein they are subjected to a gentle tumbling action within a confined space having sub- stantially the same environmental conditions as in the main cell culture reactor.

384613

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