Microchip-based acoustic trapping or capture of cells for...

G - Physics – 01 – N

Patent

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G01N 15/06 (2006.01) G01N 33/00 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2624914

The present invention provides a method and apparatus for separating by size a mixture of different size particles using ultrasound. The apparatus contains a microchannel having an acoustic transducer thereon. As a mixture of cells having different sizes flows down the microchannel, the ultrasonic radiation traps cells of desired sizes focused at nodes of a standing pressure wave in the microchannel.

L'invention concerne une méthode et un appareil pour séparer par taille un mélange de particules présentant des tailles différentes, à l'aide d'ultrasons. Cet appareil contient un microcanal présentant un transducteur acoustique monté sur celui-ci. Lorsqu'un mélange de cellules présentant différentes tailles descend en s'écoulant dans le microcanal, le rayonnement ultrasonore piège les cellules de taille voulues concentrées à des noeuds d'une onde de pression continue dans le microcanal.

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