Microcrystalline cellulose: alginate pharmaceutical suspensions

Details Microcrystalline cellulose: alginate pharmaceutical suspensions Microcrystalline cellulose: alginate pharmaceutical suspensions

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 9/00 (2006.01) A61K 31/16 (2006.01) A61K 31/167 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 33/00 (2006.01) A61K 45/08 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2291719

Novel pharmaceutical suspensions comprising a pharmaceutically active ingredient suspended in aqueous media with a suspending agent comprising attrited microcrystalline cellulose coprocessed and at least partially surface coated with a calcium sodium alginate salt complex barrier dispersant and readily dispersible and hydratable dry formulations thereof are described and exemplified.

L'invention porte sur de nouvelles suspensions pharmaceutiques comprenant un ingrédient à efficacité pharmacologique en suspension dans un milieu aqueux avec un agent de suspension comportant de la cellulose microcristalline broyée cotraitée et au moins partiellement revêtue d'un dispersant barrière formé d'un complexe d'alginates calcaires et sodiques. L'invention porte également sur leurs préparations sèches facilement dispersibles et hydratables décrites et illustrées d'exemples.

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