A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01) A61K 47/34 (2006.01)
Patent
CA 2287442
A microemulsion characterized by comprising (A) a highly polar, liposoluble medicament, a highly polar oil, and a lowly polar oil; (B) a monoester of polyglycerin with a fatty acid; and (C) a water-soluble polyhydric alcohol, the amount of the component (B) incorporated being 0.3 to 3 parts by weight based on one part by weight of the component (A), the amount of the component (C) incorporated being 0.1 to 3 parts by weight based on one part of the total amount of the components (A) and (B). The microemulsion is a highly stable microemulsion containing a highly polar, liposoluble medicament.
L'invention concerne une microémulsion, renfermant A) un médicament très polaire et très liposoluble, une huile très polaire, et une huile faiblement polaire; B) un monoester de polyglycérol avec un acide gras; et C) un polyol hydrosoluble, la quantité du constituant B) incorporé variant entre 0,3 et 3 parties en poids, sur la base d'une partie en poids du constituant A), et la quantité du constituant C) incorporé variant entre 0,1 et 3 parties en poids sur la base d'une partie de la quantité totale desdits constituants A) et B). Cette microémulsion est un microémulsion hautement stable renfermant un médicament très polaire et très liposoluble.
Hasegawa Kazuo
Nagahama Tohru
Mccarthy Tetrault Llp
Taisho Pharmaceutical Co. Ltd.
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