Microemulsion formulations comprising particular substance p...

A - Human Necessities – 61 – K

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A61K 9/107 (2006.01) A61K 31/164 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2553658

The present invention relates to dispersible pharmaceutical compositions in which the active agent is a substance P antagonist, in particular a 5-aryl- 4(R)-arylcarbonylamino-pent 2-enoic acid amide, that is useful for the treatment and prevention of respiratory diseases including asthma and chronic obstructive pulmonary disease, bowel disorders including irritable bowel syndrome (IBS), urinary incontinence, and cough.

Cette invention concerne des compositions pharmaceutiques pouvant être dispersées et dans lesquelles l'agent actif est un antagoniste de la substance P, en particulier un amide d'acide 5-aryl-4(R)-arylcarbonylamino-pent 2-anoïque, qui sert à traiter et à prévenir les maladies respiratoires telles que l'asthme et la maladie obstructive respiratoire chronique, les troubles intestinaux tels que le syndrome du côlon irritable, l'incontinence urinaire et la toux.

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