Microencapsulation of living cells

A - Human Necessities – 61 – K

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A61K 9/50 (2006.01) A61F 2/02 (2006.01) A61K 9/16 (2006.01) A61L 27/00 (2006.01) C12N 11/04 (2006.01)

Patent

CA 1258429

18 ABSTRACT OF THE DISCLOSURE Living cellular material is microencapsulated in a biocompatible semi-permeable membrane formed by interaction of aqueous solutions of poly-anionic and -cationic acrylic polymers to form water-insoluble polymer-polymer complex. An aqueous suspension of the cellular material in the polyanionic acrylic polymer is introduced in droplet form into an aqueous solution of the polycationic acrylic polymer. Examples of living cellular material include hybridoma cells and Islets of Langerhans.

498218

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