Microencapsulation of living tissue and cells

Details Microencapsulation of living tissue and cells Microencapsulation of living tissue and cells

A - Human Necessities

61

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167/104, 167/153

A61K 9/50 (2006.01) A61K 9/16 (2006.01) A61K 9/52 (2006.01) B01J 13/02 (2006.01)

Patent

CA 1196862

22 ABSTRACT OF THE DISCLOSURE Living tissue or cells, for example, islets of Langerhans, are microencapsulated for implantation in the body for long term treatment of diabetes or other disease requiring organ transplantation., The, microcapsules take the form of a biocompatible semi-permeable hydrogel membrane which permits the passage of materials and oxygen to the cells and metabolic products from the cells while retaining the cells encapsulated. The biocompatible semi-permeable membrane has an outer negatively-charged surface, which imparts to the microcapsules the ability to maintain long term effectiveness.

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