Microengineered nanospray electrode system

Details Microengineered nanospray electrode system Microengineered nanospray electrode system

H - Electricity

01

J

H01J 49/04 (2006.01) B81B 1/00 (2006.01) H01J 49/02 (2006.01) H01J 49/10 (2006.01) H01J 49/26 (2006.01) G01N 27/447 (2006.01) G01N 30/72 (2006.01)

Patent

CA 2552086

A method of aligning a nanospray capillary needle, a set of electrodes, and a capillary input to a mass spectrometer is described. The electrode system is formed using microengineering technologies, as an assembly of two separate chips. Each chip is formed on an insulating plastic substrate. The first chip carries mechanical alignment features for the capillary electrospray needle and the API mass spectrometer input, together with a set of partial electrodes. The second chip carries a set of partial electrodes. The complete electrode system is formed when the chips are assembled in a stacked configuration, and consists of an einzel lens capable of initiating a Taylor cone and separating ions from neutrals by focusing.

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