B - Operations – Transporting – 01 – J
Patent
B - Operations, Transporting
01
J
B01J 19/00 (2006.01)
Patent
CA 2624243
The invention concerns automated, inegrated microfluidic devices comprising a chemical reaction chip for performing reactions, such as the preparation of radiopharmaceutical compounds. The chip comprises an integrated microscale column and is configured for liquid flow from the column to at least one flow channel. The fluid flow is controlled by at least two on-chip valves. These double valves are configured consecutively and within proximity of 300 micrometer from each other. The reaction chamber is substantially "coinshaped", e.g. a reaction cylinder, preferably having a height diameter to height ratio greater than 3. Curved inlet and outlet channels ensure en effective elution.
L'invention porte sur un dispositif microfluidique intégré automatisé comprenant: une puce de réaction chimique capable d'effectuer une réaction chimique; une colonne à micro-échelle intégrée dans la puce et configurée pour permettre un écoulement liquide depuis la colonne jusqu'à au moins un canal d'écoulement, l'écoulement fluidique dans la colonne étant régulé par des soupapes sur la puce; et au moins deux soupapes sur la puce destinées à réguler l'écoulement fluidique dans le dispositif microfluidique.
Elizarov Arkadij M.
Kolb Hartmuth
Borden Ladner Gervais Llp
Siemens Medical Solutions Usa Inc.
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