Microfluidic devices, methods and systems for detecting...

Details Microfluidic devices, methods and systems for detecting... Microfluidic devices, methods and systems for detecting...

C - Chemistry, Metallurgy

12

M

C12M 1/34 (2006.01) B01L 3/00 (2006.01) G01N 33/553 (2006.01)

Patent

CA 2694541

Microfluidic devices methods and systems for detecting a target in a fluidic component of a sample are shown. In such devices, methods and systems, the flow resistance of various channels where the sample is introduced is adjusted to control separation of the fluidic component from the sample and/or performance of assays for the detection of the target in the fluidic com-ponent in a controlled fashion. Such performance is controlled by binding affinity of the target with capture agents or diffusion of the target in the fluidic component.

L'invention concerne des dispositifs microfluidiques, des procédés et des systèmes pour détecter une cible dans un composant fluidique d'un échantillon. Dans de tels dispositifs, procédés et systèmes, la résistance à l'écoulement de divers canaux où l'échantillon est introduit est ajustée pour réguler la séparation d'un composant fluidique de l'échantillon et/ou l'efficacité d'analyses pour la détection de la cible dans le composant fluidique de manière régulée. Une telle efficacité est obtenue par la liaison de l'affinité de la cible avec des agents de capture ou par la diffusion de la cible dans le composant fluidique.

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