Microfluidized oil-in-water emulsions and vaccine compositions

Details Microfluidized oil-in-water emulsions and vaccine compositions Microfluidized oil-in-water emulsions and vaccine compositions

A - Human Necessities

61

K

A61K 39/39 (2006.01)

Patent

CA 2521051

This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.

L'invention concerne des émulsions submicroniques d'huile dans l'eau utiles comme adjuvants de vaccins afin d'améliorer l'immunogénicité d'antigènes. L'invention concerne également des compositions de vaccins qui contiennent un antigène associé à ces émulsions intrinsèquement ou extrinsèquement, ainsi que des procédés de préparation des émulsions et des vaccins.

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