Microlaboratory devices and methods

Details Microlaboratory devices and methods Microlaboratory devices and methods

B - Operations, Transporting

01

L

B01L 3/00 (2006.01) B01J 19/00 (2006.01) B81B 1/00 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2403278

Disclosed herein are apparatuses and devices, and methods for using and making the same, for use in performing desired activities in an automated, microscale format. Microparticles are ushered about within a microscale apparatus, to selectively move between various stations in a selected order and manner. Some embodiments include reaction, micro-weighing, micro-analysis, reagent acquisition and deposition, and incubation stations. Microparticles can individually move, or move as trains. Samples, including particulate and solid tissue samples may be manipulated and analyzed within the device. Some embodiments may engage in micro-fabrication activities or micro-deconstruction activities. Systems for controlling such apparatuses are included as well as methods of operation.

L'invention concerne des appareils et des dispositifs, ainsi que des proc~d~s servant ~ utiliser et ~ fabriquer ces derniers, servant ~ ex~cuter des activit~s d~sir~es dans un format automatis~ ~ l'~chelle microscopique. On introduit des microparticules ~ l'int~rieur d'un appareil ~ l'~chelle microscopique, de mani­re ~ les faire se d~placer entre diff~rentes stations selon un ordre et un mode s~lectionn~s. Quelques modes de r~alisation consistent ~ effectuer une r~action, une micro-pond~ration, une micro-analyse, une acquisition et un d~pÙt de r~actif, et en des stations d'incubation. Ces microparticules peuvent se d~placer individuellement ou se d~placer collectivement en trains de microparticules. On peut manipuler et analyser dans ce dispositif des sp~cimens, y compris des sp~cimens de particules et de tissus solides. Quelques modes de r~alisation peuvent englober des activit~s de micro-fabrication ou de micro-d~construction. L'invention concerne ~galement des syst­mes servant ~ commander ces appareils et des proc~d~s de mise en application.

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