A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 37/00 (2006.01) A61K 9/00 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2698632
In order to produce a microneedle array which includes a macromolecular drug such as a vaccine antigen and insulin at its acral portion using a water-soluble thread-forming polymer for a base, there is a need for a substrate which enables a solvent to be efficiently removed so that a base dense solution containing a target substance can be dried and cured while still inserted in a mold. This problem is resolved by using a porous water-insoluble substrate or a porous filter as a substrate, which allows drying and curing as well as peeling from a female mold to be carried out while the base dense solution containing a target substance is still filled in the mold.
Pour fabriquer une puce de micro-aiguilles comprenant un matériau polymère fibreux soluble dans l'eau à titre de base et un médicament du type polymère, par exemple, un antigène vaccinal ou l'insuline, contenu dans les pointes, il est souhaitable d'utiliser un substrat qui permette de sécher et de durcir un dopant de base contenant la substance souhaitée en éliminant efficacement le solvant de celui-ci, tout en conservant le dopant inséré dans une matrice. L'utilisation d'un substrat poreux insoluble dans l'eau ou d'un film poreux à titre de substrat a permis de sécher et de durcir un dopant de base contenant une substance souhaitée, tout en maintenant le dopant inséré dans une matrice femelle, et de détacher le substrat de la matrice.
Bioserentach Co. Ltd.
Marks & Clerk
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