Micronization method

Details Micronization method Micronization method

C - Chemistry, Metallurgy

07

D

C07D 451/00 (2006.01) A61K 31/46 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2631949

The invention relates to a method for producing a micronized, virtually anhydrous form of (1.alpha.,2~,4~,5.alpha.,7~)-7-[(hydroxydi-2- thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide, said form per se, and the use thereof for producing a medicament, especially a medicament having an anticholinergic effect.

L'invention concerne un procédé de production d'une forme micronisée et presque anhydre de bromure de (1.alpha.,2ß,4ß,5.alpha.,7ß)-7-[(hydroxydi-2-thiénylacétyl)oxy]-9,9-diméthyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane, la forme en tant que telle ainsi que son utilisation dans la production d'un médicament, en particulier dans la production d'un médicament à effet anticholinergique.

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