Microoganism for producing fk-506

Details Microoganism for producing fk-506 Microoganism for producing fk-506

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) C12N 1/20 (2006.01) C12P 17/18 (2006.01) C12P 19/44 (2006.01)

Patent

CA 2059706

9836P/0800A Case 18239 TITLE OF THE INVENTION NEW PROCESS FOR PRODUCING FK-506 ABSTRACT OF THE DISCLOSURE Described is a new process for producing the macrolide immunosuppressant, FK-506 under fermentation conditions utilizing the microorganism, Streptomyces sp., (Merck Culture Collection No. MA 6858) ATCC No. 55098. The immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transplants.

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