Microorganism growth

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/06 (2006.01) C12M 1/24 (2006.01) C12M 1/34 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2092301

2092301 9303178 PCTABS00019 A method of monitoring the growth of microorganisms in liquid culture involving the detection of pressure change in a gas-tight container such as a blood culture bottle incorporating a flexible diaphragm (septum) by detecting displacement of the septum, is characterised by the position or conformation of the diaphragm being repeatedly sensed using a distance-measuring means, such as a laser, preferably capable of detecting a variation in the position or conformation of the diaphragm to an accuracy of 200 µ or better, with a portion of the container adjacent the diaphragm conveniently being used as a reference to detect any relative positional or conformational change of the diaphragm. Preferably the laser repeatedly scans a plurality of containers mounted in a holder such as a flat bed or a carousel.

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