Microorganism of genus chrysosporium for use in preparing...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/14 (2006.01) A61K 31/66 (2006.01) C07J 53/00 (2006.01) C12P 33/00 (2006.01)

Patent

CA 2211167

A Chrysosporium strain No. CBS 123.95, mutants and derivatives thereof, and a method for preparing non-peptide compounds using said strain, are disclosed. Novel compounds of general formula (I), pharmaceutical compositions containing same, and the use of said compounds in anticancer treatments, are also disclosed.

La présente invention concerne une souche de Chrysosporium numéro CBS 123.95 et ses mutants ou dérivés et un procédé de préparation de composés non peptidiques mettant en oeuvre ladite souche. Elle se rapporte également à de nouveaux composés définis par une formule générale (I), à des compositions pharmaceutiques les contenant et à leur utilisation dans les traitements anti- cancéreux.

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