Microorganism producing cyclic compound

Details Microorganism producing cyclic compound Microorganism producing cyclic compound

C - Chemistry, Metallurgy

12

N

C12N 1/14 (2006.01) A61K 36/06 (2006.01) A61K 38/00 (2006.01) A61P 3/10 (2006.01) A61P 17/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2718394

A miciroorganisim which produces compounds useful as an antifungal agent, particularly a therapeutic agent for deep-seated mycoses, such as mycotic sinusitis, is provided. The present inventors have conducted intensive studies on naturally-occurring microorganisms as a research for antifungal compounds, and found a fungus Acremonium persicinum which produces cyclic compounds having a potent antifungal activity and useful as a medicament, particularly an antifungal agent, and the present invention was completed.

L'invention concerne un microorganisme qui produit un composé utile comme agent antifongique, plus particulièrement un agent thérapeutique pour une mycose profonde, par exemple, un agent thérapeutique pour une sinusite mycosique. Dans le cadre de la recherche pour des composés ayant un effet antifongique, des microorganismes d'origine naturelle ont été examinés en profondeur et, en conséquence, le champignon Acremonium persicinum produisant un composé cyclique qui possède une activité antifongique favorable et peut être utile comme produit pharmaceutique, en particulier comme agent antifongique, a été découvert et utilisé pour l'invention.

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